The origin of plasma neutrophil gelatinase-associated lipocalin in cardiac surgery
نویسندگان
چکیده
منابع مشابه
The economic impact and cost-effectiveness of urinary neutrophil gelatinase-associated lipocalin after cardiac surgery.
BACKGROUND Acute kidney injury (AKI) is common after cardiac surgery, and expeditious recognition with specific biomarkers may help improve outcome. OBJECTIVE Because the economic impact of a biomarker-based diagnostic strategy is unknown, we assessed the cost-effectiveness of using urinary neutrophil gelatinase-associated lipocalin (NGAL) for the diagnosis of AKI after cardiac surgery compar...
متن کاملNeutrophil gelatinase-associated lipocalin: a promising biomarker for detecting cardiac surgery-associated acute kidney injury.
Acute kidney injury is a common and significant problem that occurs in a wide variety of clinical settings. Cardiac surgery-associated acute kidney injury continues to be a well-recognized complication of cardiac surgery with associated morbidity and mortality. A lack of early biomarkers for acute kidney injury has prevented timely interventions to mitigate the effects of acute kidney injury. B...
متن کاملAssessing the Prediction Power of Plasma Neutrophil Gelatinase-Associated Lipocalin and Serum Cystatin C for Diagnosis Kidney Damage
Background & Objective: Chronic Kidney Disease (CKD) has been recognized as a serious public health threat. The early detection of kidney damage in CKD is a useful way to reduce the disease burden. This study aimed to determine the power of Neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (Cys-C) to predict the kidney damage in Iranian patients. Materials & Methods: This st...
متن کاملNeutrophil Gelatinase-Associated Lipocalin Levels During Pneumoperitoneum
BACKGROUND AND OBJECTIVES A temporary deterioration in renal function during pneumoperitoneum has been reported, but the extent is not known. A new marker for the early detection of renal injury, neutrophil gelatinase-associated lipocalin (NGAL), has been shown to increase in various conditions that affect renal function. This study was conducted to explore detrimental effects of pneumoperitone...
متن کاملDual action of neutrophil gelatinase-associated lipocalin.
Neutrophil gelatinase-associated lipocalin (NGAL) is expressed and secreted by immune cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts bacteriostatic effects, which are explained by its ability to capture and deplete siderophores, small iron-binding molecules that are synthesized by certain bacteria as a means of iron acquisition. Consistently, NGAL deficien...
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ژورنال
عنوان ژورنال: BMC Nephrology
سال: 2019
ISSN: 1471-2369
DOI: 10.1186/s12882-019-1380-4